IMAGE

Fig. 6

ID

ZDB-IMAGE-260427-94

Genes

d2EGFP
mRuby

Antibodies

Ab1-ctnnb

Publication

Lardennois et al., 2026 - Two distinct modes of Vgll4-mediated Tead regulation control organ size in zebrafish

All Figures

Figures for Lardennois et al., 2026

Image

Figure Caption

Fig. 6 Yap1 transcriptional activity is detected in the pLLP prior to the onset of migration.

a–b” Single-plane confocal images of the pLLP in control embryos at 32 hpf (a) and at 20 hpf (b) showing GTIIC:d2EGFP expression. cxcr4b:Lifeact-mRuby is used to visualize the pLLP (a’, b’). Merged images of the two channels are shown in (a”, b”). Single-plane confocal images of the pLLP in 20 hpf embryos (c), injected with tBFP-yap1 mRNA (d), yap1 Mo (e), or vgll4b sg1+2 (f), showing GTIIC:d2EGFP (c–f), β-catenin (c’–f’), and merged channels (c”-f”). β-catenin is used to visualize the pLLP. g Quantification of GTIIC:d2EGFP positive cells in the pLLP of 20 hpf and 32 hpf control embryos (N = 1 independent replicate). Mean gray value measured either on the whole image (h) or within the pLLP on a single plane (i) in the GFP channel in the same embryos for each condition (N ≥ 1 independent replicates). Data are presented as mean ± SD. Unpaired t-tests (Mann–Whitney) were conducted. Scale bar: 20 μm (a–f”).

Figure Data

Expression / Labeling details

Phenotype details

Acknowledgments

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