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Fig. 2

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Publication: Cervino et al., 2026 - Sulfatase modifying factors control the timing of zebrafish convergence and extension morphogenesis
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Fig. 2 C&E defects in zebrafish gastrulae with altered sulfatase modifying factor levels.
A Representative images of whole mount in situ hybridization (WISH) for tbxta (notochord), dlx3b (neural plate border) and egr2b (rhombomeres 3 & 5) in tailbud stage (10 hpf) zebrafish embryos of the indicated conditions. WT control, MZsumf2-/-, and all OE embryos are on the AB background, MZsumf1-/- embryos are on the TU background. Anterior is up in all images, lateral views are shown on top, dorsal views on bottom. Scale bar = 100 μm. B, C Anteroposterior (AP) axis length (B, yellow arrowheads) and notochord width (C, magenta lines) of embryos depicted in (A). Each dot represents a single embryo, N number of independent experiments, n number of embryos. Means and standard deviation are indicated; *p < 0.05, * p < 0.01, ****p < 0.0001 compared to WT control group by Kruskal–Wallis and Dunn’s multiple comparisons tests. Source data are provided as a Source Data file.

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