FIGURE

Fig. 2

ID

ZDB-FIG-260526-65

Publication

Cervino et al., 2026 - Sulfatase modifying factors control the timing of zebrafish convergence and extension morphogenesis

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Fig. 2

C&E defects in zebrafish gastrulae with altered sulfatase modifying factor levels.
A Representative images of whole mount in situ hybridization (WISH) for tbxta (notochord), dlx3b (neural plate border) and egr2b (rhombomeres 3 & 5) in tailbud stage (10 hpf) zebrafish embryos of the indicated conditions. WT control, MZsumf2-/-, and all OE embryos are on the AB background, MZsumf1-/- embryos are on the TU background. Anterior is up in all images, lateral views are shown on top, dorsal views on bottom. Scale bar = 100 μm. B, C Anteroposterior (AP) axis length (B, yellow arrowheads) and notochord width (C, magenta lines) of embryos depicted in (A). Each dot represents a single embryo, N number of independent experiments, n number of embryos. Means and standard deviation are indicated; *p < 0.05, * p < 0.01, ****p < 0.0001 compared to WT control group by Kruskal–Wallis and Dunn’s multiple comparisons tests. Source data are provided as a Source Data file.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sumf1^{la015919Tg/la015919Tg} (TU) sumf2^{bcm126/bcm126} (AB)
Observed In:	axis convergent extension involved in gastrulation notochord
Stage:	Bud

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Nat. Commun.