FIGURE

FIGURE 2

ID

ZDB-FIG-210530-16

Publication

Gong et al., 2021 - Claudin h Is Essential for Hair Cell Morphogenesis and Auditory Function in Zebrafish

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FIGURE 2

Loss function of claudin h caused the defects of otic vesicle and otoliths. (A,D) Imaging analysis of otic vesicle and otoliths in control and claudin h knocking down groups at 72 and 96 hpf. The yellow dotted line marked the boundary of the otic vesicle. Scale bar = 50 μm. (B,C) The statistical analysis of otic vesicle area in the control and claudin h morphants at 72 and 96 hpf. (E) Quantification of zebrafish embryos with abnormal otolith (defects in both number and shape of otoliths: claudin h morphants lost the utricle otolith or had a unnormal saccular otolith). Each bar represents the mean ± SE. Values with **** above the bars are significantly different (P < 0.0001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO4-cldn3c
Knockdown Reagent:	MO4-cldn3c
Observed In:	lapillus otic vesicle otolith sagitta
Stage Range:	Protruding-mouth to Day 4

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol