FIGURE

FIGURE 5

ID

ZDB-FIG-220921-42

Publication

He et al., 2022 - Tibetan medicine salidroside improves host anti-mycobacterial response by boosting inflammatory cytokine production in zebrafish

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FIGURE 5

Tnfα is required for SAL-mediated protective effects during mycobacterial infection. (A) Representative images for the distribution of M. marinum (Wasabi) in different groups of zebrafish embryos at 72 hpi. Scale bar: 200 μm. (B) Statistics of normalized green fluorescence intensity in A. One-way ANOVA was applied for the comparison. (C) Survival rates of M. marinum-infected zebrafish tnfα^−/− embryos treated with various concentrations of INH and SAL. n = 20 per group. A, B, and C: data are representative of three independent repeats.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB tnfa^{zf3218/zf3218}
Conditions:	bacterial treatment by injection: Mycobacterium marinum bacterial treatment by injection: Mycobacterium marinum, chemical treatment by environment: Salidroside
Observed In:	defense response to bacterium whole organism
Stage Range:	Long-pec to Days 14-20

Phenotype Detail

Acknowledgments

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