ZFIN is now using GRCz12tu for Genomic Data
Gene
junbb
- ID
- ZDB-GENE-040426-2666
- Name
- JunB proto-oncogene, AP-1 transcription factor subunit b
- Symbol
- junbb Nomenclature History
- Previous Names
-
- junbl
- wu:fa95h09
- wu:fj44e11
- wu:fj68b07
- zgc:63933
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within fin regeneration and lymph vessel development. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including Kupffer's vesicle; fin; nervous system; optic vesicle; and pectoral fin bud. Human ortholog(s) of this gene implicated in head and neck squamous cell carcinoma and melanoma. Orthologous to human JUNB (JunB proto-oncogene, AP-1 transcription factor subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 29 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63933 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Kiesow et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR004827 | Basic-leucine zipper domain |
| Domain | IPR005643 | Jun-like transcription factor |
| Family | IPR002112 | Transcription factor Jun |
| Family | IPR050946 | AP-1 Transcription Factor bZIP |
| Homologous_superfamily | IPR008917 | Transcription factor, Skn-1-like, DNA-binding domain superfamily |
| Homologous_superfamily | IPR046347 | Basic-leucine zipper domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | AP-1 Transcription Factor bZIP | Basic-leucine zipper domain | Basic-leucine zipper domain superfamily | Jun-like transcription factor | Transcription factor Jun | Transcription factor, Skn-1-like, DNA-binding domain superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:Q7T3E3 | InterPro | 310 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers