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Phenotype Figure Summary
Marker:
polr3a
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Lubash
et al.
, 2026
Fig 1
polr3a
sa907/+
(AB)
, 
polr3a
sa907/sa907
(AB)
branchiostegal ray decreased size, abnormal
cranial cartilage decreased size, abnormal
entopterygoid decreased size, abnormal
head morphology, abnormal
opercle decreased size, abnormal
ventral mandibular arch morphology, abnormal
whole organism
polr3a
expression decreased amount, abnormal
Fig 2
polr3a
sa907/sa907
; ir937Tg (AB)
ceratobranchial cartilage decreased size, abnormal
Meckel's cartilage decreased size, abnormal
Fig 3
polr3a
sa907/sa907
; b1212Tg (AB)
dentary decreased length, abnormal
dentary increased width, abnormal
maxilla Ab19-gfp labeling decreased distribution, abnormal
maxilla decreased size, abnormal
maxilla decreased volume, abnormal
opercle Ab19-gfp labeling decreased distribution, abnormal
opercle decreased volume, abnormal
opercle osteoblast decreased volume, abnormal
Fig 4
polr3a
sa907/sa907
; ir937Tg (AB)
ceratobranchial 1 cartilage apoptotic process increased process quality, abnormal
ceratobranchial 2 cartilage apoptotic process increased process quality, abnormal
Fig 5
polr3a
sa907/sa907
(AB)
head ab14-h3 labeling decreased distribution, abnormal
head apoptotic process increased process quality, abnormal
head cell population proliferation decreased process quality, abnormal
Fig 6
polr3a
sa907/sa907
(AB)
whole organism 5S class rRNA transcription by RNA polymerase III decreased process quality, abnormal
whole organism ribosome biogenesis decreased process quality, abnormal
whole organism tRNA transcription by RNA polymerase III decreased process quality, abnormal
Fig 7
polr3a
sa907/sa907
(AB)
whole organism
aars1
expression increased amount, abnormal
whole organism
atf4b
expression increased amount, abnormal
whole organism
cdkn1a
expression increased amount, abnormal
whole organism
chac1
expression increased amount, abnormal
whole organism
mdm2
expression increased amount, abnormal
whole organism
polr3a
expression decreased amount, abnormal
whole organism
tp53
expression increased amount, abnormal
Fig 8
polr3a
sa907/+
(AB)
, 
polr3a
sa907/sa907
(AB)
head apoptotic process increased process quality, abnormal
opercle decreased volume, abnormal
whole organism
cdkn1a
expression increased amount, abnormal
whole organism
polr3a
expression decreased amount, abnormal
whole organism
tp53
expression increased amount, abnormal
Fig. S1
polr3a
sa907/sa907
(AB)
whole organism Ab1-polr3a labeling decreased amount, abnormal
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