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Phenotype Figure Summary
Marker:
pex1
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Heins-Marroquin
et al.
, 2025
FIGURE 1
pex1
lux4/lux4
(AB)
liver
pex1
expression absent, abnormal
FIGURE 2
pex1
lux4/lux4
(AB)
liver increased size, abnormal
liver lipid increased amount, abnormal
liver vacuole increased amount, abnormal
ovary degenerate, abnormal
whole organism viability, abnormal
FIGURE 3
pex1
lux4/lux4
(AB)
brain phytanic acid increased amount, abnormal
brain ultra-long-chain fatty acid increased amount, abnormal
brain very long-chain fatty acid increased amount, abnormal
hepatocyte peroxisomal matrix Ab5-cat labeling decreased amount, abnormal
hepatocyte peroxisomal membrane Ab3-abcd3 labeling decreased amount, abnormal
liver phytanic acid increased amount, abnormal
liver ultra-long-chain fatty acid increased amount, abnormal
liver very long-chain fatty acid increased amount, abnormal
FIGURE 4
pex1
lux4/lux4
(AB)
liver lipid increased amount, abnormal
whole organism dihydroceramide increased amount, abnormal
whole organism phosphatidylcholine increased amount, abnormal
whole organism phytanic acid increased amount, abnormal
whole organism pristanic acid increased amount, abnormal
whole organism triglyceride increased amount, abnormal
FIGURE 5
pex1
lux4/lux4
(AB)
whole organism
arf4b
expression increased amount, abnormal
whole organism
hpxa
expression decreased amount, abnormal
whole organism
hspa5
expression increased amount, abnormal
whole organism
isg15
expression increased amount, abnormal
whole organism
rida
expression decreased amount, abnormal
whole organism
scd
expression increased amount, abnormal
FIGURE 6
pex1
lux4/lux4
(AB)
retinal cone cell Ab2-arr3a labeling spatial pattern, abnormal
swimming behavior decreased process quality, abnormal
FIGURE 7
pex1
lux4/lux4
(AB)
retinal cone cell cone photoreceptor outer segment disorganized, abnormal
retinal outer nuclear layer decreased thickness, abnormal
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