CRISPR

CRISPR6-opa1

ID
ZDB-CRISPR-250507-3
Name
CRISPR6-opa1
Previous Names
None
Target
Sequence
5' - TGCGGGAAAGACTAGTGTGC - 3'
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Disclaimer
Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.
Note
None
Genome Resources
None
Target Location
Constructs
No data available
Genomic Features
Genomic Feature Affected Genomic Regions
ucd16 opa1
Expression
Gene expression in Wild Types + CRISPR6-opa1
No data available
Phenotype
Phenotype resulting from CRISPR6-opa1
No data available
Phenotype of all Fish created by or utilizing CRISPR6-opa1
Phenotype Fish Conditions Figures
aerobic respiration decreased occurrence, abnormal opa1ucd16/ucd16 standard conditions FIGURE 8 with image from Strachan et al., 2025
whole organism opa1 expression decreased amount, abnormal opa1ucd16/ucd16 standard conditions FIGURE 2 with image from Strachan et al., 2025
cranial nerve II mitochondrion circular, abnormal opa1ucd16/ucd16 standard conditions FIGURE 6 with image from Strachan et al., 2025
cranial nerve II mitochondrial crista decreased amount, abnormal opa1ucd16/ucd16 standard conditions FIGURE 6 with image from Strachan et al., 2025
cranial nerve II mitochondrion decreased size, abnormal opa1ucd16/ucd16 standard conditions FIGURE 6 with image from Strachan et al., 2025
cranial nerve II mitochondrion decreased length, abnormal opa1ucd16/ucd16 standard conditions FIGURE 6 with image from Strachan et al., 2025
optokinetic behavior decreased rate of occurrence, abnormal opa1ucd16/ucd16 standard conditions FIGURE 2 with image from Strachan et al., 2025
optokinetic behavior decreased rate of occurrence, abnormal WT + CRISPR5-opa1 + CRISPR6-opa1 standard conditions FIGURE 2 with image from Strachan et al., 2025
retinal outer nuclear layer EGFP expression decreased amount, abnormal WT + CRISPR5-opa1 + CRISPR6-opa1 standard conditions FIGURE 6 with image from Strachan et al., 2025
retinal ganglion cell layer EGFP expression decreased amount, abnormal WT + CRISPR5-opa1 + CRISPR6-opa1 standard conditions FIGURE 6 with image from Strachan et al., 2025
retinal inner plexiform layer EGFP expression decreased amount, abnormal WT + CRISPR5-opa1 + CRISPR6-opa1 standard conditions FIGURE 6 with image from Strachan et al., 2025
whole organism opa1 expression decreased amount, abnormal opa1ucd16/+ standard conditions FIGURE 2 with image from Strachan et al., 2025
Citations
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