FIGURE

Fig 6

ID

ZDB-FIG-250203-29

Publication

Li et al., 2025 - Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos

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Fig 6

PGRP5 plays an important role in neurobehavioral alteration and oxidative stress in zebrafish embryos.

(A) The movement tracks of zebrafish at 5 dpf larvae that exposed to mock and PGRP5-KD conditions. Three representative photographs are shown in each group. (B) The total distance moved of zebrafish larvae that both in control and PGRP5-KD conditions. (C) The average velocity of zebrafish larvae that both in mock and PGRP5-KD conditions. (D) Detection the contents of ROS, along with enzymatic activities of CAT, SOD and AChE in larval zebrafish that both in mock and PGRP5-KD conditions. The values are presented as means ± SEM (Each value contains at least four biological replicates, and each biological replicate contains three technical replicates). *, p < 0.05; **, p < 0.01. (E) The behavioral trajectory characteristics of zebrafish under 10 μM minocycline drug exposure. (F-G) The total distance and mean velocity of zebrafish larvae that exposed to mock and 10 μM minocycline.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB AB + MO2-pglyrp5
Condition:	chemical treatment by environment: minocycline
Knockdown Reagent:	MO2-pglyrp5
Observed In:	swimming behavior whole organism acetylcholinesterase activity whole organism catalase activity whole organism reactive oxygen species whole organism superoxide dismutase activity
Stage Range:	Protruding-mouth to Day 5

Phenotype Detail

Acknowledgments

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