FIGURE

Fig. 1.

ID

ZDB-FIG-250219-43

Publication

Gjorcheska et al., 2025 - Sox10 is required for systemic initiation of bone mineralization

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Fig. 1.

Mineralization deficit in zebrafish sox10 mutants. (A) Example images illustrating a major delay in initiation of bone mineralization in sox10 mutants between 3 and 7 dpf revealed by Alizarin Red staining. Some mineralization is present by 5 dpf but never achieves control levels before lethality at 8 dpf. (B) Schematic representation of the affected mineralized structures and their embryonic origins. (C,D) Von Kossa (C) and OsteoImage (D) staining showing absent calcium deposition and hydroxyapatite formation in sox10 mutants at 4 dpf and gradual recovery starting at 5 dpf. Arrowheads point to the opercle (op). Numbers in panels indicate the proportion of larvae of that genotype with the presented phenotype. Scale bars: 100 µm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	sox10^{ci3020/ci3020}
Observed In:	bone mineralization
Stage Range:	Protruding-mouth to Days 7-13

Phenotype Detail

Acknowledgments

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