FIGURE

FIGURE 5

ID

ZDB-FIG-250407-47

Publication

Tatzl et al., 2025 - Deficiency of the Synaptic Adhesion Protein Leucine-Rich Repeat Transmembrane Protein 4 Like 1 Affects Anxiety and Aggression in Zebrafish

Other Figures

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FIGURE 5

Neurotransmitter and brain metabolome changes in lrrtm4l1^−/− zebrafish. Telencephalic levels of (a) homovanillinic acid, (b) adenosine, (c) serotonin and (d) melatonin as measured by targeted metabolomics in lrrtm4l1^−/− (Hom) and lrrtm4l1^+/+ (WT) zebrafish. n = 10/group. Student's t test. Data are presented as violin plots with the horizontal black line indicating the median. (e) Volcano plot displaying metabolites detected by untargeted metabolomics. Metabolites with adjusted p‐values below 0.05 and a log2fold change ≥ |1| were regarded as significant. (f) Spectral matching of detected metabolites. (g) Violin plot displaying telencephalic levels of a metabolite similar to methyl vanillate. n = 9–10/group.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	lrrtm4l1^{sa21708/sa21708}
Observed In:	telencephalon adenosine telencephalon homovanillic acid telencephalon melatonin telencephalon methyl vanillate telencephalon serotonin
Stage:	Adult

Phenotype Detail

Acknowledgments

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