FIGURE

Fig. 7

ID

ZDB-FIG-250729-94

Publication

Wu et al., 2025 - Mitochondrial dysfunction is driven by imbalanced fission and fusion of mitochondria in myofibrillar myopathy type 5

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Fig. 7

Schematic representation of the direct interaction between filamin-C, Drp1, and F-actin during mitochondrial fission, as well as the consequences of filamin-C deficiency. In the absence of filamin-C, Drp1 remains unactivated, leading to impaired mitochondrial fission. This disruption in fission subsequently results in mitophagy and mitochondrial dysfunction.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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