FIGURE

Fig. 2

ID

ZDB-FIG-260427-90

Publication

Lardennois et al., 2026 - Two distinct modes of Vgll4-mediated Tead regulation control organ size in zebrafish

Other Figures

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Fig. 2

A Tead-Binding-Deficient Yap1 mutant fails to rescue yap1 loss-of-function phenotype.

MIP of confocal Z-stacks showing differences in pLLP size in uninjected yap1^+/+ embryos (a), yap1^+/+ embryos injected with yap1-WT mRNA (b), uninjected yap1^−/− embryos (c), yap1^−/− embryos injected with yap1-WT mRNA (d), yap1^+/+ embryos injected with yap1-S54A mRNA (e), yap1^−/− embryos injected with yap1-S54A mRNA (f). Quantification of pLLP cell number (g, i) and aspect ratio (h, j) of the pLLP in the indicated conditions (N = 3 independent replicates). Data are presented as mean ± SD. Unpaired t-tests (Mann–Whitney) were conducted. Scale bar: 20 μm.

Expression Data

Gene:	EGFP
Fish:	yap1^fu48/fu48; zf106Tg/zf106Tg
Anatomical Term:	posterior lateral line primordium
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	yap1^fu48/fu48; zf106Tg/zf106Tg
Observed In:	posterior lateral line homeostasis of number of cells within a tissue posterior lateral line tissue morphogenesis posterior lateral line primordium
Stage:	Prim-15

Phenotype Detail

Acknowledgments

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